While people can be creative anywhere, some places do launch everyone who tunes into them. I think Caroline Collective is such a place in Houston. And I think that companies and cities which want to be seen as creative centers have to heed what we've learned. But there are no guarantees, as discussed in this article.
NY Times: When Art and Energy Were SoHo Neighbors, 2011-Apr-28, by Michael Kimmelman
The grid had obviously been important to earlier generations of New York artists, just as the flotsam and jetsam of the city had been to older Fluxus artists. But for the settlers of SoHo it helped inspired the creative rebirth of a neighborhood.